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These findings are preliminary and entirely preclinical

Neurologic symptoms The neurologic symptoms of vitamin B 12 deficiency are myriad and include numbness and tingling of the hands and, more commonly, the feet (peripheral neuropathy)

Vitamin B12 is involved in the metabolism of every cell of the human body, especially affecting DNA synthesis and regulation, but also fatty acid synthesis and energy production

Theoretical concerns about chronic peptide administration including potential immunogenicity (antibody formation), accumulation in tissues, or long-term effects on neuroendocrine regulation have not been systematically addressed

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