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Description

As a key mechanism for eliminating drugs from the body, studying metabolism is essential for understanding the pharmacodynamic mechanisms of drugs in vivo

Subject terms: Cancer stem cells, Cancer metabolism, Drug development, Cancer microenvironment, Tumour biomarkers Introduction Cancer stem cells (CSCs) exhibit self-renewal capacity, enhanced survival mechanisms, and resistance to conventional therapies, leading to tumor relapse and progression

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TrAC - Trends Anal Chem 26:227238 Acknowledgments The authors gratefully acknowledge Marie-Josphe Dcret, Lionel Dussoul, Jean-Claude Gondrexon, Sylvie Michaud, and Herv Nunge for their technical assistance