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Aging Cell 6:607618 Le Bourg E (2005) Hormetic protection of Drosophila melanogaster middle-aged male flies from heat stress by mildly stressing them at young age

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Ultrafiltration, precipitation with solvents and liquid chromatography techniques (e.g., ion exchange, gel filtration) have been proposed for purification of peptides, however, their current implicit high costs make them prohibitive for large scale applications