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Commonly observed adverse effects include abdominal discomfort, bloating, flatulence, and diarrhea, which generally diminish as the hosts system acclimates to the microbial intervention (552)

Recognition of PAMPs or DAMPs triggers a cascade of events, called PAMP-triggered immunity (PTI), which includes ion fluxes across the plasma membrane, generation of ROS, activation of mitogen-activated protein kinases (MAPKs) and transcriptional activation of genes

doi: 10.1016/j.cell.2018.08.041 144 SinghDAgarwalV

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