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An animal study found that exogenous GSH improved sperm motility and testicular morphology without affecting blood sugar or body weight, suggesting that exogenous GSH has organ-specific effects without affecting diabetes-related metabolic abnormalities []

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This enables efficient modification even under conditions that mimic the complex cellular environment, thus suggesting the feasibility of extending BIVID-MaP to intracellular applications, although further optimization of the VQ-conjugated compounds, including improvements in membrane permeability, is still needed

The use of DNMTi within NAc reversed CUMS-induced depression-like behavior and decreased GDNF expression, and DNA methylation and methyl CpG binding protein 2 binding were also increased in stress-resilient C57BL/6J mice 136