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However, without simultaneous reduction of obesity, the remarkable resistance to developing steatosis in hepatocyte Cul3-deficient mice paradoxically caused profound systemic insulin resistance

Citation library: 103,510 references behind our interaction content, 65,311 of them resolved to verified PubMed/DOI sources

Since several amino acids emerged among the best discriminating metabolites in 1 H-NMR analyses, we employed a targeted UPLC/MS approach to better evaluate the serum amino acids profile of PD patients

Senomorphics: Modulating the Senescence-Associated Secretory Phenotype (SASP) Unlike senolytic therapies that aim to directly eliminate senescent cells, senomorphics work by modulating the senescence-associated secretory phenotype (SASP), which consists of pro-inflammatory cytokines, chemokines, growth factors, and extracellular matrix-degrading enzymes secreted by senescent cells

J Hematol Oncol 17:119