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CAS 42464-96-0 uniquely identifies the compound 5-Amino-1MQ for accurate chemical documentation and research reproducibility

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FIGURE 9 The core of this toxicity mechanism lies in the depletion of the labile Fe 2+ pool (Figure 5B)without altering total cellular iron (Figure 5A)which triggers a compensatory iron-starvation response (IREB2, TfR1, Ferritin

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Methods We conducted an untargeted 1 H NMR-based metabolomic analysis of serum in a clinically defined cohort of patients with genetic forms of PD (n = 119) and age- and sex-matched HCs (n = 48)