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Voltage-gated ion channels that mediate membrane excitability and action potential generation and propagation are highly sensitive to ion gradients and membrane polarization

41, 11031130 [DOI] [PubMed] [Google Scholar] 23.Tee A.R., Manning B.D., Roux P.P., Cantley L.C

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But as a supplement it has beneficial properties for the organism

Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)