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Uric acid and oxidative stress

Glutathione also enhances the effectiveness of Vitamin C, a complementary antioxidant

Microglia provide such intermediates to OPCs during remyelination 110 , and this can occur through transfer of lipid-containing extracellular vesicles (EVs) 114

Disrupted iron homeostasis in the brain has been increasingly implicated in the pathology of many CNS diseases, where excessive iron accumulation can lead to oxidative stress, neuroinflammation, and ferroptotic cell death in vulnerable brain regions (Salvador et al., 2010)

The influx of eosinophils peaked between day 25 and 30 p.i., when approximately 70% of all viable cells were eosinophils, and subsequently declined, despite a continued increase in lesion size over time (Fig