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Mean values are based on one kitten per replicate, seven replicates in CON and LMSM, and six replicates in HMSM on d 35 and d 65

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& De Camilli, P

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212,213 Statins are well-known inhibitors of HMG-CoA reductase (HMGCR) and are commonly used as cholesterol-lowering medications to prevent and/or treat atherosclerosis

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Beyond that, to be considered an effective tool, the gene variant must be closely related to the risk factor of interest and not directly influence the outcome, but only through exposure ( Figure 1 )

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