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Proper conformation restriction can be used to control the ligand conformation and make the molecule biased to the desired conformation binding with the target proteins as too many free rotation bonds of drug molecules are not conducive for binding [29, 30]

It has shown promise in managing: Leaky gut syndrome Gastritis and ulcers Irritable Bowel Syndrome (IBS) Inflammatory Bowel Disease (IBD) Stress-related gut dysfunction Gut-mediated mood imbalance and brain fog By restoring gut integrity, it enhances nutrient absorption, immune balance, and emotional well-being

Frontiers in Pharmacology, 12, 627533.

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