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J Mol Biol 268:869885

The electron density was of high enough quality to differentiate several main chain second positions and multiple alternative side chain positions in both structures

The reason: since the fragment contains only the C-terminal part, it lacks the binding domains for GHR (most of the affinity of hGH for GHR lies in the central part of the molecule)

Open-label, randomized phase II trial with BNT111 and cemiplimab in combination or as single agents in patients with Anti-PD-1-refractory/Relapsed, unresectable stage III or IV melanoma (2020)

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