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Frequent epigenetic inactivation of the RASSF1A tumour suppressor gene in testicular tumours and distinct methylation profiles of seminoma and nonseminoma testicular germ cell tumours

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The direct comparison of the transcriptomes of the two NaNO 2 treated cultures revealed that glucose utilization genes, lipid biosynthesis genes, siderophore cluster genes, Cazyme genes, glutathione S-transferase (GST) genes, and ammonia assimilation genes showed higher transcriptional activity, while ribosome biogenesis genes showed lower transcriptional activity in the 135 mM treated cultures than in the 90 mM treated group (Additional files 2 and 6)