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Use of cells expressing subunit variants to identify diverse mechanisms of AMPK activation

This approach inevitably excludes some less-studied conditions, particularly those with very small patient populations or those that have only recently been the focus of pharmaceutical interest, but it nonetheless captures the lions share of DHT investment and innovation in the rare disease space

Centrifuge at 14,000 rpm for 10 minutes at 4 C

doi: 10.1038/s41467-017-02490-4 127 ZhangY-WCaoM-MLiY-JLuP-PDaiG-CZhangMet al