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For example, in Alzheimer's disease research, isogenic neuron models established for APP and PSEN1 mutations have successfully reproduced early pathological changes such as A deposition and tau phosphorylation 10

Control of ifn-gamma production and regulatory function by the inducible nuclear protein ikappab-zeta in T cells

The 2025 narrative review noted that despite the volume of preclinical work, well-controlled human trial data are scarce, and the regenerative findings should be interpreted accordingly (PMID 40789979)

In parallel, tocopheryl glucoside, a stable, water-soluble derivative of vitamin E, contributes to sustained cellular antioxidant defense by promoting the regeneration of intracellular vitamin E 14