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According to et al

The end result is gastric atrophy and depletion of intrinsic factor leading to poor absorption of food-bound, free, and biliary vitamin B 12 .2 Malabsorption is more complete and severe in PA compared to food-cobalamin malabsorption which is more partial in nature,2 and so the manifestations are more overt and severe in PA

This compound is recognized for its repair signaling properties, with its natural presence diminishing with age [13]

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Another study using an animal hemorrhoid model suggests that extracts from Cissus quadrangularis may act as dual inhibitors of arachidonic acid metabolism, thus exhibiting potent anti-inflammatory properties