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DNA strand breaks were then labelled with tetramethylrhodamine (TMR) red for 1 h at 37 C

Within QSEA, the MeDIP enrichment was calibrated with 450k methylation array measurements of primary hepatocytes (GSM999339) and cardiac myocytes (HCM, GSM999381) from ENCODE 70 , for the hepatic and cardiac micro tissues respectively

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This mechanism becomes especially important during times of increased energy demand, like exercise or fasting

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