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Chronic rapamycin treatment causes glucose intolerance and hyperlipidemia by upregulating hepatic gluconeogenesis and impairing lipid deposition in adipose tissue

Antagonism of GHRH, with either intracerebroventricular administration of OCT or a competitive GHRH receptor antagonist during the light phase, caused suppression of sleep and reduced Fos+GAD immunoreactive cell counts in the MnPN and VLPO