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RNA (1 g) was processed and hybridized onto the Human Exon 1.0 ST array (Affymetrix Inc., Santa Clara, CA, USA) according to the manufacturer's protocol as previously described [15]

Disruption of this microbiome-host symbiosis contributes to the initiation and progression of immune and metabolic diseases, such as IBD 73 , graft-versus-host diseases (GvHD) 74 , and type 2 diabetes 75 , underlining the proposition that microbe-host interactions are critically important for human health 76