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The distribution of these isomers can influence physicochemical properties such as solubility, stability, and antioxidant activity, and may therefore affect bioavailability and biological function

5,61 As an example, orally administered GSH ethyl ester is able to significantly raise GSH concentrations in the liver, kidney, spleen, pancreas, heart, and lung of the mouse, and in human red blood cells, skin fibroblasts, and several lymphoid cell lines

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AAP NPs achieve COC targeting relying on the PBA-SA interaction, so AAP NPs will inevitably bind to SA on non-cancerous cells, posing a low but inevitable risk of off-target binding

Additionally, 19 studies were considered as low quality(score5), 79 studies were considered as medium quality(510)