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A vegan diet is generally healthy, low in cholesterol and protective of heart disease, but its followers must take vitamin B12 supplements or risk a condition that causes permanent numbness in their hands and feet, experts say

This is one reason most IGF-1 LR3 protocols avoid late-evening dosing dosing close to bedtime is more likely to coincide with the natural overnight GH pulse

Long-term oncologic safety remains an open research question because the same migration-promoting and pro-angiogenic activity that supports wound closure has, in some murine melanoma models, correlated with increased metastasis

Finally, we outline a translational roadmap integrating multi-omics profiling, functional metabolomics, and spatial biology to match metabolic vulnerabilities with precision therapies

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