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NMR Combined extraction of polar and lipophilic metabolites was carried out using methanol/water/chloroform as suggested by the Standard Metabolic Reporting Structures working group (47)

The association of the GSG-Index with increased liver enzymes was assumed to be due to increased glutathione transamination by GGT, releasing glutamate

Once it reaches the last part of the small intestine, the ileum, its absorbed from the GI tract where B12 detaches from IF and joins transcobalamin to become B12 TC-II

Ibuprofen is a non-steroidal anti-inflammatory drug, commonly referred to as an NSAID

In the experimental group, the 2 min of ultrasound irradiation (1 MHz, 1 W/cm 2 ) was performed at different time points