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3.7 Anticancer mechanisms of phenolic acids 3.7.1 Apoptosis induction and suppression of angiogenesis and metastasis Phenolic acids are a major class of plant-derived polyphenols (non-flavonoid type) widely present in fruits, vegetables, teas, coffee, and other foods

KD has been shown in in vitro studies to regulate histone deacetylases (HDAC1, HDAC3, and HDAC4)