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While exosome-loaded si-SCD1 accelerates ATC cell death by ROS accumulation [138]

This synergistic effect is likely attributable to LDRT-induced intracellular generation of HO through water radiolysis, with the elevated HO serving as a key substrate for Cu-mediated Fenton-like reactions

11 JiaY.LiJ.WangY.MaY.ChenL.ZhangH.et al

doi: 10.1038/s41580-023-00648-1 20 UrsiniFMaiorinoM

[55] have suggested that the relative stability of methionine is due to the complicated kinetics of MAT-I and MAT-III and we have confirmed this by model experiments [56]