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For example, neurons typically catabolize gamma-aminobutyric acid (GABA) to create NADH to support biosynthetic processes and breast tumor cells with a GABAergic phenotype have a strong growth advantage in the brain by converting GABA to succinate to boost the citric acid cycle (153)

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To determine how the circadian clock affects mitochondrial metabolism in adipose tissue, we isolated mitochondria from the gonadal white adipose tissue (gWAT) of male mice entrained to a normal or inverted light cycle at different times of the night and day (zeitgeber time (ZT))