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In vitro models for glaucoma research: effects of hydrostatic pressure

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Its active form, 1,25(OH)2D, regulates mucosal immunity, host defense, and inflammation by binding to the vitamin D receptor (VDR) in macrophages [73, 74], triggering the expression of the antimicrobial peptide cathelicidin (CAMP) (LL-37) and promoting autophagosomelysosome fusion and maturation [16, 75]

As discussed earlier, the conventional cancer therapies include chemotherapy, radiotherapy, bone marrow transplant, and surgical interventions, but these therapies have drawbacks and limitations

However, despite displaying promising results, some of them also have serious side effects, such as nephrotoxicity (Kalinowski and Richardson, 2005)