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Additionally, MRP2 contains a 100-residue long linker between NBD1 and TMD2, resembling the regulatory (R) domain of the cystic fibrosis transmembrane regulator (CFTR)

and 5-TGGCAAATTCCATGGCACC-3 (sense) and 5-AGAGATGATGACCCTTTTG-3 (antisense) to detect GAPDH mRNAs

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Platinum-based drugs: cisplatin/Platinol, oxaliplatin/Eloxatin, carboplatin/Paraplatin Taxanes: paclitaxel/Taxol, docetaxel/Taxotere, cabazitaxel/Jevtana Thalidomide and its relatives: carfilzomib/Kyprolis, lenalidomide/Revlimid, pomalidomide/Pomalyst, apremilast/Otezla Epothilones: ixabepilone/Ixempra Proteasome inhibitor: bortezomib/Velcade Vinca alkaloids: vincristine/Marqibo, vinblastine/Velbane The neuropathy caused by most of these drugs commonly shows up weeks or months after treatment has ended

Incubation of acetone with homogenates of nasal mucosa from mice indicated that acetone was metabolized via a NADPH-dependent pathway in vitro , but no evidence of in vivo metabolism of acetone by the upper respiratory tract was found in mice, rats, guinea-pigs or hamsters (Morris, 1991 )