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Arf6 (wt)-, Arf6 (Q67L)-, and Arf6 (T27N)-HA/pcDNA3 plasmids were respectively used as templates to amplify cDNA for Arf6-overexpression (Arf6-OE)

Journal of Clinical Investigation 79 , 15641570, doi: 10.1172/jci112990 (1987)

1 Introduction Incidence rates of type 2 diabetes (T2D) have reached pandemic proportions, affecting more than 422 million individuals worldwide ( Figure 1 )