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In the pathogenesis of CVDs, the metabolism of BCAAs and their associated signaling pathways play a critical role

Cardiotoxicity of sorafenib is mediated through elevation of ROS level and CaMKII activity and dysregulation of calcium homoeostasis

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As shown by Vilaplana et al., ibuprofen treatment significantly increases the survival rate of Mtb-infected mice (173) ( Table 2 )