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PMID 30317438

The difference did not achieve statistical significance, except in the sublingual group, where the decrease was of borderline significance

Dizziness and fatigue Memory loss, difficulty in concentrating, and cognitive difficulties Anemia or iron deficiency anemia Muscle cramps Shortness of breath Erratic moods and possible signs of mental health disorders such as depression Irregular or halted menstruation Inflamed tongue Low energy Hair Your Vitamin B12 deficiency may also be a symptom in itself of other diseases such as SIBO ( Small Intestinal Bacterial Overgrowth ) or other gut-related disorders

Yes, prolonged B12 deficiency can cause potentially irreversible neurological damage, including subacute combined degeneration of the spinal cord

You may find relief from your acid reflux symptoms with alkaline water