To ensure that the compounds identified in our parent and pDC-based assays were specific inhibitors of the interaction between STX7 and Munc13-4 but did not interfere with vesicle docking and exocytosis by inhibiting RabsMunc13-4 complexes, ENDO compounds were counterscreened in TR-FRET assays using lysates expressing FlagMunc13-4 and EGFPRab27a or EGFPRab11
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CAS Number 946870-92-4 Molecular Formula C400H625N111O115S9 Molecular Weight 9117.5 g/mol Appearance White lyophilised powder Sequence MFPAMPLSSLFVNGPRTLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA Need Help
Palma E, Mendes F, Morais GR, Rodrigues I, Santos IC, Campello MPC, Raposinho P, Correia I, Gama S, Belo D, Alves V, Abrunhosa AJ, Santos I, Paulo A (2017) Biophysical characterization and antineoplastic activity of new bis(thiosemicarbazonato) Cu(II) complexes
The enlargement of the lumina of bronchi and terminal bronchioles characterizes the canalicular stage, in addition to the formation of capillaries at the site of the future air space and the appearance of surfactant, representing the major developments that are absolutely crucial to extra-uterine life
