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Studies show that combining topical and oral glutathione delivers superior results than a single treatment method

Inhibition of melanosome transfer A number of studies have previously proposed regulatory mechanisms of melanosome movement in dendrites and interplay between keratinocytes and melanocytes during the transfer process (124,125)

Chem Res Toxicol 12:223229 Marshall KA, Reist M, Jenner P, Halliwell B (1999) The neuronal toxicity of sulfite plus peroxynitrite is enhanced by glutathione depletion: implications for Parkinsons disease

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Fig.4 Typical calibration curve of GSSG Fig.5 Typical calibration curve of GSH The concentration of glutathione can be determined by either Kinetic method or Pseudo-end point method