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Description

Korsgaard N, Aalkjaer C, Heagerty AM, Izzard AS, Mulvany MJ

Mater Lett 131:194197

indicates that lactate upregulates the expression of NUSAP1 through lysine lactylation modifications, thereby forming a NUSAP1-LDHA-glycolysis-lactate conduit loop

Furthermore, epigenetics play a role in influencing risk factors for CVD, including but not limited to age, hypertension, smoking, excessive alcohol consumption, and diabetes