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eNeuro 4:81

Am J Med Genet 49:118124 Friedreich N (1863) Ueber degenerative Atrophie der spinalen Hinterstrnge

It is referred to as automitocrine signaling (11)

Reports that newborns with a complete lack of insulin effects due to inactivating defects in the INSR gene can now survive for extended time into adolescence when treated with recombinant IGF-I, that stimulate glucose uptake via the IGF1R sharing common signaling pathways with the INSR, support an important direct role of IGF-1 signaling on metabolism (93)