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Zinc Zinc is an indispensable trace element that is important for homeostasis and acts as a cofactor for several enzymes involved in many biological and life processes, like skeletal development, antioxidant defense system, and immune response (106, 182)

Nicola JP, Peyret V, Nazar M et al (2015) S-nitrosylation of NF-B p65 inhibits TSH-induced Na+/I symporter expression

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NPHP is manifested by polyuria, impaired sodium reabsorption that causes hypovolemia and hyponatremia, anemia, and growth delay