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These results suggest that metformin may serve as a promising therapeutic agent for alleviating OA pain and slowing the progression of OA in MIA-induced mouse model, which is consistent with the results of a previous study 42

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| 2025 | Curr Rev Musculoskelet Med 3 4Pharmacokinetics of growth hormone-releasing hormone(1-29)-NH2 and stimulation of growth hormone secretion in healthy subjects after intravenous or intranasal administration | Wilton et al

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PIN1 inhibitors synergize with CDK4 inhibitors against TNBC in human cells and immune-compromised mouse models Selective CDK4/6 inhibitors have emerged as effective ER + BC treatment but only have limited efficacy in TNBC, in which RB gene loss occurs predominantly 48,49