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Torsional energy calculations were performed using an online torsional energy calculator 1 based on input dihedrals, which uses a combined quantum chemical ( 2 , 3 , 2 ) and empirical calculation ( 1 , 1 ) described in detail elsewhere (Haworth et al., 2010)

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Results from in vitro tests demonstrated that sustained delivery of both curcumin and puerarin lasted for 6 hours in non-reducing conditions and 5 hours in reducing conditions