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Description

In conclusion, we have identified a novel NADPH- and glutathione-dependent pathway through which TCA cycle activity impacts ER homeostasis

Pharmacokinetics of GW433908, a prodrug of amprenavir, in healthy male volunteers

10.1016/j.phymed.2023.154682 51 HaoD

Although glutathione did not significantly affect survival rates, its ability to reduce toxicity and allow more complete treatment cycles could indirectly contribute to better long-term outcomes