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Transcriptomic analysis of induced pluripotent stem cells (iPSCs) carrying an A53T SNCA mutation and a triplication discovered that the expression of mitochondrial function-related genes was perturbed (Zambon et al., 2019), which could explain the observed reduction in mitochondrial respiration, aberrant mitochondrial morphology, and decreased mitochondrial membrane potential

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10.1016/j.ejphar.2019.01.030 59 SikiricP.HahmK

The present review discusses the biology of the CD38 enzyme and the current state of development of pharmacological tools aim at CD38 and explores how these agents may represent a novel approach to treat human conditions including cancer, metabolic diseases and diseases of aging

How many sessions of chelation therapy are typically needed