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This review synthesizes epidemiological data, comparative metagenomic analyzes, and mechanistic studies to demonstrate that stone formers exhibit reduced -diversity, depletion of oxalate-degrading taxa (e.g., Oxalobacter , Lactobacillus , Bifidobacterium ), and enrichment of pro-inflammatory genera ( Escherichia , Bacteroides )

Long-term continuous N -carbamylglutamate treatment in frequently decompensated propionic acidemia: a case report

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Safety and effectiveness of metformin in patients with reduced renal function: a systematic review

[22] [23] Special populations require particular consideration: Pregnancy and breastfeeding : There is insufficient evidence regarding safety during pregnancy and lactation