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289 :138629 Corresponding authors: Professor Shougang Zhuang, Ph.D., M.D., Department of Medicine, Rhode Island Hospital and Alpert Medical School, Brown University, 593 Eddy St, Providence, Rhode Island, 02903, USA

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Prebiotic fibers (especially derived short-chain fatty acids) , probiotics, polyphenols, glutamine, methionine, vitamin D and zinc can, in contrast, enhance barrier integrity