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Olson, K

Amanda MS, Boman GI, Marcus CM, Carrie H-L, William JM

This possibility has been directly assessed by Kim et al, 2008 [77] who used a knock-in mouse model in which wild-type MORs were replaced with a mutant receptor capable of undergoing rapid morphine-dependent sequestration [27]

[DOI] [PubMed] [Google Scholar] [128]

These tumorigenic cells are like adult or embryonic stem cells in their ability to self-renew and give rise to a diversity of cells that differentiate and after a finite number of divisions, eventually succumb to programmed cell death