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CuAOs are homodimers (70 to 95 kDa per subunit) and each contains a single active site composed of a Cu ion and the 2,4,5-trihydroxyphenylalanine quinone (TPQ) as cofactor (Dove and Klinman 2001

Vitamin D The final one I will talk about here is Vitamin D, which is essential for absorption of calcium and phosphorus (and hence bone and teeth development)

Antioxidants (vitamins C, A, E, and alpha-lipoic acid) Antioxidants help neutralize reactive oxygen species generated during Phase 1, reducing oxidative damage to liver cells and surrounding tissues

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173 Notably, DGK has been shown to promote the synthesis of PA from DAG, which can subsequently be used to generate LPA in fibrotic tissues, thus negatively impacting the efficacy of radiation therapy