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On the other hand, evaluation of possible toxicity of these medicinal plants/natural products is also important as these medicines are directly applied in eyes and can have not just potential benefits but also harmful effects

In addition, five redox biomarkersSuperoxide Dismutase (SOD), Total Antioxidant Capacity (TAC), Catalase (CAT), Glutathione Peroxidase (GPX), and Total Thiol Levels (TTLs)along with nitrosative and oxidative stress markers, nitrate (NO , as a proxy for nitric oxide) and malondialdehyde (MDA), were also assessed

& Khariwala, S

Biochim Biophys Acta 1822(5):657663

The therapeutic efficacy of the internalization mechanism is rooted in the mitochondrias ability to produce ATP, while the non-internalization mechanism is based on the idea that mitochondria can interact with specific substances on the cell surface to transmit information and stimulate cellular self-preservation (188, 189)