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Notably the association between GGT and cardiovascular mortality was not significant in the subgroup of Asian participants [relative risk =1.76 (0.763.30)] (36)

Treatment of the second aliquot with TCEP and IAM, followed by measurement of CAM-S-CAM-TPP after protein precipitation, gave the total amount of RSS /RS(S) n S present in the tissue homogenate, giving values that are consistent with earlier reports of overall tissue levels of persulfides using sulfane sulfur atom trapping 31,32

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demonstrated that macrophages can absorb extracellular lactate to promote the lactylation of high mobility group box-1 (HMGB1), which is subsequently secreted via exosomes, increasing endothelial permeability and inducing further endothelial barrier dysfunction [163]

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