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In conclusion, the metabolism of many amino acids (including Cys, Met, etc.) is involved in the regulation of iron death, which may be a new target for the treatment of iron death-related diseases

MIF-driven activation of macrophages induces killing of intracellular Trypanosoma cruzi dependent on endogenous production of tumor necrosis factor, nitric oxide and reactive oxygen species

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Apaf-1 functions not only in apoptosis but also as an evolutionarily conserved cytosolic DNA sensor