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Poor glycaemic control increases this risk further, particularly when hyperglycaemia is chronic or poorly managed over several years

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The AUCs for VCTE in detecting F2, F3 and F4 were 0.889, 0.928, and 0.939 with optimal cut-offs (Youden Index) of 8.8 kPa, 12.2 kPa, and 16.8 kPa

Its presence in exosomes could encode the hosts miRs and downregulate some host genes required for viral evasion processes (108), as elevated levels of miR-B1-5p and miR-B1-3p in urinary exosomes indicate possible BKV infection (109, 110)

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