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The primary mechanism involves the inactivation of GPX4, leading to lipid peroxidation and excessive ROS accumulation, which ultimately results in ferroptosis 39,40

The outer membrane protein TbpA and the surface lipoprotein TbpB work together to extract iron from human transferrin, with TbpA forming the channel for iron transport across the membrane and TbpB acting as an initial binding partner that enhances iron release and transferrin removal

They are also observed during root regeneration after decapitation

Starting at a lower dose, gradually increase it based on each person's response and tolerance

10.1016/j.jtemb.2022.127061 229 ZhangM.LiaoX.JiG.FanX.WuQ