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Lactic acid not only inhibits the proliferation and activation of immune cells, but also promotes the differentiation of regulatory T cells, thus weakening the anti-tumor immune response

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Ayton and his colleagues demonstrated that elevated metal levels in the inferior temporal lobe promote glial cell activation, redox imbalance, and iron-dependent neuronal death, thereby accelerating memory decline in patients with Alzheimers disease (Ayton et al., 2020)