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Conventional approaches for treatment Conventional therapies for beta thalassemia major include lifelong blood transfusion, iron chelation and splenectomy

Myhill and coworkers [21] used an Adenosine Triphosphate (ATP) profile test (see Appendix) in neutrophils to establish mitochondrial dysfunction in ME/CSF patients

Consistently, the SNU-16 secretome significantly increased Ucp1 expression, whereas the MKN74-derived secretome did not induce this effect [Supplementary Figure 1B]

10.3136/fstr.FSTR-D-21-00264 160

(e) The 10 B-loaded agents must be chemically and metabolically stable and (f) must not feature any systemic cytotoxicity